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Glucagonoma

A type of functional pancreatic NET.

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Glucose

A sugar found in many foods and in normal blood; the main source of energy for most living organisms.

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Grade

A system of classifying tumor cells. The cells are graded based on how they look under a microscope and how quickly the tumor is likely to grow and spread. Low-grade tumors (grades 1 and 2) look like the tissue around them. They are less aggressive. High-grade tumors (grades 3 and 4) do not look like the tissue around them. They are more aggressive.

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Growth Hormone- Releasing Factor (GRF)

A chemical released by the brain that tells the pituitary gland to produce growth hormone.

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Hepatic Chemoembolization

Also known as hepatic artery embolization (HAE) or trans arterial embolization (TACE). A therapeutic method used to treat primary liver tumors, and cancer tumors that have spread to the liver (metastatic liver tumors).

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Histamine

A natural hormone produced and stored within the body. It is a part of the body’s immune response and is released during an allergic reaction. Symptoms of gastrointestinal NETs (GI-NETs) may be caused by an excessive release of histamine.

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Hormone

A substance, usually a protein, that is released and travels through the bloodstream to different organs. Hormones help control how some of the organs in the body work.

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Hyperglycemia

The condition of having high levels of glucose (sugar) in your blood. Symptoms include dry mouth, thirst, frequent urination (including at night), blurry vision, and dry, itchy skin.

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Hypochlorhydria

The condition of having low levels of hydrochloric acid in your stomach. Symptoms include halitosis (bad breath), heartburn, bloating or belching, gas right after eating, and indigestion.

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Hypoglycemia

The condition of having low levels of glucose (sugar) in your blood. Symptoms include dizziness, headache, tiredness, and confusion.

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Insulin

A hormone released by the pancreas that lowers glucose (sugar) levels in your blood.

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Hypokalemia

The condition of having low levels of potassium (salt) in your blood. It may be caused by diarrhea.

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Interferon

A substance that can improve the body’s natural response to infections and other diseases. Interferons can help stop cancer cells from diving to form new cancer cell and can slow down the growth of tumors. The body normally produces interferon. It can also be made in the laboratory to treat cancer and other diseases.

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Intraoperative Radiation Therapy (IORT)

Radiation therapy that is given during surgery.

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Irradiation

Also called total body irradiation (TBI)- This treatment method gives radiotherapy to the whole body. It uses high-energy radiation to destroy cancer cells and shrink tumors.

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Irritable Bowel Syndrome

A group of symptoms—including pain or discomfort in the abdomen and changes in bowel movement patterns—that occur together.

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Islet Cell Tumor

A term used for a pancreatic NET (PNET).

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Ki-67 Index

A protein used to diagnose and assess the prognosis of tumors including NETs. The Ki-67 index measures how much of this protein is present in cancer cells. The results may allow doctors to grade NETs, and predict how likely they are to grow or spread.

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Lanreotide

A medicine used for treating NETs. Lanreotide belongs to a group of drugs called somatostatin analogues. These are man-made proteins that are similar to a hormone in the body called somatostatin.

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Laparoscopy

A surgical procedure where a thin, lighted tube is inserted through an incision to inspect inside the body.

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