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Biopsy

A procedure where a small amount of tissue is removed from the body and examined under a microscope or using other tests to find out if there is a tumor.

 

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Bone Scan (Bone Scintigraphy)

An imaging test that uses a very small amount of radioactive dye to help diagnose problems in the bones. It involves an injection with a radioactive substance called a radionuclide. A bone scan may also be called bone scintigraphy, a radionuclide scan, or a nuclear medicine scan.

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Bronchial NETs

NETs that develop in the lungs. There are two types depending on where they occur. Central bronchial NETs are located in trachea (windpipe) and around the main central area of the lungs. Peripheral bronchial NETs are in the outer areas of the lungs. Bronchial NETs are the second most common cause of carcinoid syndrome. Bronchial NETs may also be referred to as bronchial carcinoids or bronchial carcinoid tumors.

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Bronchodilator

An agent that causes an increase in the opening of the airway passages in the respiratory system.

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Bronchoscope

A thin, flexible fibre-optic instrument that has a light source and a viewing device or camera on the end and is used to look inside the airways.

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Bronchoscopy

A nonsurgical procedure that is used to look inside a person’s airways inside the lungs using a bronchoscope.

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CAPTEM (Capecitabine and Temozolomide)

Chemotherapy treatment for advanced metastatic and high grade neuroendocrine tumors.

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Carcinoid

An outdated term used for Neuroendocrine Tumor or GEP-NET. (Separate from Carcinoid Crisis and Carcinoid Syndrome)

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Carcinoid Crisis

Carcinoid crisis is a dangerous condition that can occur at the time of surgery. It is characterized by a drop in blood pressure, sometimes accompanied by an abnormally fast heart rate. Carcinoid crisis can be fatal.

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Carcinogenesis

The process by which normal cells become cancer cells.

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Carcinoid Heart Disease

A specific variety of heart disease that can come from not regulated or prolonged Carcinoid Syndrome. Carcinoid heart disease can cause part of the heart to become obstructed by fibrous deposits, limiting its ability to pump. The exact cause is unknown, but doctors suspect that excess serotonin in the body may play a role.

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Carcinoid Syndrome

A set of symptoms that occur when a functional NET that releases the hormone serotonin begins to spread or metastasize. The symptoms may be sudden or severe. This is not to be confused with Serotonin Syndrome which is caused by the use of certain serotonergic medications or drugs.

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Carcinoid Tumors or Carcinoids

A type of neuroendocrine tumors (NETs). The term is used to describe gastrointestinal NETs or gastroenteropancreatic NETs (GEP-NETs).

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Carcinoma

Cancer that starts in the skin or in tissues that line or cover internal organs.

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Catecholamines

A type of neurohormone (a chemical that is made by nerve cells and used to send signals to other cells). Catecholamines are also a collective term for the hormones epinephrine, norepinephrine, and dopamine. High levels of catecholamines in the urine or blood may indicate the presence of NETs.

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Chemoembolization

Injection of a chemotherapeutic drug into a blood vessel, along with an agent that causes the vessel to close, ensuring that the chemotherapeutic agent remains concentrated in the organ supplied by the vessel.

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Chemotherapy

The use of drugs to destroy cancer cells, usually by affecting their ability to grow.

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Chromogranin A or CgA

A protein that is secreted by neuroendocrine tissues. It may be used as a marker in blood tests or tissue samples to detect NETs. It is one of the most important tumor markers for gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

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Chronic

Persisting over a long period of time.

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Colonoscopy

A test that examines of the inside of the colon (gut). During this test a thin, tube-like instrument called a colonoscope is inserted into the anus and passed up inside the gut. The colonoscope has a very small light and video camera at the end for viewing the inside of the gut.

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