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Mitotic Count / Mitotic Rate

The process by which a pathologist counts the number of cells dividing within a specified amount of cancer tissue. Along with a Ki-67% value, Mitotic Rate helps to determine the aggressiveness of the cancer cells.

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Monoclonal Antibody

Substitute antibodies produced in a lab that can help the immune system fight unwanted cells, such as cancer cells.

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Multimodal

Using a variety of methods to evaluate or accomplish a task.

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Multimodal Therapy

Combines more than one method of treatment. Surgery with chemotherapy and radiation therapy is a common treatment approach for cancer. Immunotherapy and gene therapy, can also be added.

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NAFLD

Nonalcoholic Fatty Liver Disease can lead to liver inflammation and progress to cirrhosis or liver failure.

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Neoplasm

A tissue mass that forms when cells grow and divide abnormally. See also: NEN, NET and NEC

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Paraganglioma

A type of neuroendocrine tumor that forms near certain blood vessels and nerves outside of the adrenal glands. Frequently over releases certain hormones in response to stress.

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Peritoneal Carcinomatosis

A site of Neuroendocrine metastasis which gives the appearance of sandpaper on the peritoneum membrane. Can be widespread or sporadic. Not to be confused with Peritoneal Carcinoma (which is not a Neuroendocrine metastasis diagnosis).

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Peritoneum

A membrane which lines the abdominal cavity and covers a majority of the organs contained within the abdomen. Multi-layered, the Parietal Peritoneum lines the pelvic and abdominal cavities while the Visceral Peritoneum covers the surfaces of most of the abdominal organs.

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PHEO / PARA

An abbreviation for Pheochromocytoma and Paraganglioma which are Neuroendocrine tumors associated with the Adrenal Glands.

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Pheochromocytoma

A rare type of neuroendocrine tumor that develops in the adrenal glands. It releases hormones that may cause high blood pressure, headache, sweating and symptoms of a panic attack.

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Physiological Uptake

Phrase used by radiologists to describe naturally occurring metabolic activity which might mistakenly be interpreted as a radiotracer uptake.

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PICC (Peripherally Inserted Central Catheter)

A long term IV administration for antibodies, blood draws, nutrition, and medications.

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Quality of Life

A person’s perceived emotional, physical, material, and social well-being.

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Radiotracer Uptake

A quantitative measurement of the radiopharmaceutical drugs (radiotracer) used in nuclear medicine to highlight internal organs. The uptake value is not always an indication of progression or a success rate.

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Receptor Positive

Abbreviated expression within the Neuroendocrine community when discussing treatments requiring SSTR2.

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Rectal NETs

A primary Neuroendocrine tumor located in the final part of the large intestine, the rectum, which is where the colon attaches to the anus.  Recent increased frequency of diagnosis is typically attributed to earlier colon cancer screening practices.

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